Efficacy of Locally Sourced Herbal Extracts as Adjuncts to Non-Surgical Periodontal Therapy: A Randomized Trial

Abstract

Periodontal disease remains a significant public health concern affecting millions worldwide, with conventional non-surgical periodontal therapy serving as the primary treatment modality. This randomized controlled trial evaluated the efficacy of locally sourced herbal extracts as adjunctive therapy to scaling and root planing in patients with chronic periodontitis. A total of 120 participants were randomly allocated into four groups: control group receiving standard non-surgical periodontal therapy alone, and three experimental groups receiving additional local application of neem (Azadirachta indica), turmeric (Curcuma longa), or green tea (Camellia sinensis) extracts. Clinical parameters including probing pocket depth, clinical attachment level, gingival index, and plaque index were assessed at baseline, 3 months, and 6 months post-intervention. Microbiological analysis of subgingival plaque samples was conducted to evaluate the antimicrobial efficacy against periodontal pathogens. Results demonstrated statistically significant improvements in all clinical parameters across experimental groups compared to the control group, with turmeric extract showing the most pronounced effects. The findings suggest that locally sourced herbal extracts can serve as effective, economical, and accessible adjuncts to conventional periodontal therapy, particularly in resource-limited settings. This study provides evidence-based support for integrating traditional botanical medicine with modern periodontal treatment protocols.